Self-Assembly of a DNA-Based Switchable Linker for Single-Molecule Force Spectroscopy
نویسندگان
چکیده
منابع مشابه
Nanoengineering a single-molecule mechanical switch using DNA self-assembly.
The ability to manipulate and observe single biological molecules has led to both fundamental scientific discoveries and new methods in nanoscale engineering. A common challenge in many single-molecule experiments is reliably linking molecules to surfaces, and identifying their interactions. We have met this challenge by nanoengineering a novel DNA-based linker that behaves as a force-activated...
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ژورنال
عنوان ژورنال: Biophysical Journal
سال: 2012
ISSN: 0006-3495
DOI: 10.1016/j.bpj.2011.11.982